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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 956851.

Science Communication

COLOTAN Symposia

The COLOTAN 1st Symposium “Colon targeting of drugs: current state of the art” – click to find symposium presentations and recording.

The COLOTAN 2nd Symposium “Drug disposition in the colon” – click to find symposium presentations and recording.

The COLOTAN 3rd Symposium “Gut disorders and possible impact on colonic drug targeting” – click to find symposium presentations and recording.

The COLOTAN 4th Symposium “Targeted drug delivery in the gastrointestinal tract: current status, emerging techniques and blue sky thinking” – click to find symposium programme.

 

COLOTAN Journal Articles

  1. L. E. McCoubrey, A. Favaron, A. Awad, M. Orlu, S. Gaisford, A. W. Basit, Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics, Journal of Controlled Release 2023, DOI: 10.1016/j.jconrel.2022.12.029
  2. A. L. Nichols, Z. Blumenfeld, L. Luebbert, H. J. Knox, A. K. Muthusamy, J. S. Marvin, C. H. Kim, S. N. Grant, D. P. Walton, B. N. Cohen, R. Hammar, L. L. Looger, P. Artursson, D. A. Dougherty, H. A. Lester, Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane, Journal of Neuroscience, 2023, DOI: https://doi.org/10.1523/JNEUROSCI.1519-22.2022
  3. R. Hammar, M. E. Sellin, P. Artursson, Epithelial and microbial determinants of colonic drug distribution, European Journal of Pharmaceutical Sciences, 2023, DOI: 10.1016/j.ejps.2023.106389
  4. C. Tannergren, H. Jadhav, E. Eckernäs, J. Fagerberg, P. Augustijns, E. Sjögren, Physiologically based biopharmaceutics modeling of regional and colon absorption in humans, European Journal of Pharmaceutics and Biopharmaceutics, DOI: 10.1016/j.ejpb.2023.03.013
  5. L. Gnatzy, G. Ismailos, M. Vertzoni, C. Reppas, Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106510
  6. H. Jadhav, P. Augustijns, C. Tannergren, Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products, Molecular Pharmaceutics, 2023, DOI: 10.1021/acs.molpharmaceut.3c00683, download paper.
  7. K. T. Kopp, L. Saerens, J. Voorspoels, G. Van den Mooter, Solidification and oral delivery of biologics to the colon- A review, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106523
  8. V. Barmpatsalou, M. Tjakra, L. Li, I.R. Dubbelboer, E. Karlsson, B. Pedersen Lomstein, C.A.S. Bergström, Development of a canine artificial colonic mucus model for drug diffusion studies, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2024.106702
  9. A. Favaron, E. Turkgeldi, M. Elbadawi, S. Gaisford, A. W. Basit, M. Orlu, Do probiotic interventions improve female unexplained infertility? A critical commentary. Reproductive BioMedicine Online, DOI: 10.1016/j.rbmo.2023.103734
  10. A. Favaron, L. E. McCoubrey, M. Elbadawi, A. W. Basit, M. Orlu (2023). The ageing microbiome, pharmaceutical considerations, and therapeutic opportunities. Pharmaceutical Formulations for Older Patients, 191–230, DOI: 10.1007/978-3-031-35811-1_8 
  11. I. Parente, L. Chiara, F. Gaiani, G. L. de’Angelis, E. Barocelli, S. Bertoni, P110 Heterogeneous response of colonoid-derived monolayers to TNFα and IFNγ exposure: functional and morphological characterization, Journal of Crohn’s and Colitis, Volume 18, Issue Supplement_1, January 2024, Page i394, DOI: 10.1093/ecco-jcc/jjad212.0240