This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 956851.

Science Communication

COLOTAN Symposia

The COLOTAN 1st Symposium “Colon targeting of drugs: current state of the art” – click to find symposium presentations and recording.

The COLOTAN 2nd Symposium “Drug disposition in the colon” – click to find symposium presentations and recording.

The COLOTAN 3rd Symposium “Gut disorders and possible impact on colonic drug targeting” – click to find symposium presentations and recording.

The COLOTAN 4th Symposium “Targeted drug delivery in the gastrointestinal tract: current status, emerging techniques and blue sky thinking” – click to find symposium programme.


  • L. E. McCoubrey, A. Favaron, A. Awad, M. Orlu, S. Gaisford, A. W. Basit, Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics, Journal of Controlled Release 2023, DOI: 10.1016/j.jconrel.2022.12.029
  • A. L. Nichols, Z. Blumenfeld, L. Luebbert, H. J. Knox, A. K. Muthusamy, J. S. Marvin, C. H. Kim, S. N. Grant, D. P. Walton, B. N. Cohen, R. Hammar, L. L. Looger, P. Artursson, D. A. Dougherty, H. A. Lester, Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane, Journal of Neuroscience, 2023, DOI:
  • R. Hammar, M. E. Sellin, P. Artursson, Epithelial and microbial determinants of colonic drug distribution, European Journal of Pharmaceutical Sciences, 2023, DOI: 10.1016/j.ejps.2023.106389
  • C. Tannergren, H. Jadhav, E. Eckernäs, J. Fagerberg, P. Augustijns, E. Sjögren, Physiologically based biopharmaceutics modeling of regional and colon absorption in humans, European Journal of Pharmaceutics and Biopharmaceutics, DOI: 10.1016/j.ejpb.2023.03.013
  • L. Gnatzy, G. Ismailos, M. Vertzoni, C. Reppas, Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106510
  • H. Jadhav, P. Augustijns, C. Tannergren, Approaches to Account for Colon Absorption in Physiologically Based Biopharmaceutics Modeling of Extended-Release Drug Products, Molecular Pharmaceutics, 2023, DOI: 10.1021/acs.molpharmaceut.3c00683, download paper.
  • K. T. Kopp, L. Saerens, J. Voorspoels, G. Van den Mooter, Solidification and oral delivery of biologics to the colon- A review, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106523
  • V. Barmpatsalou, M. Tjakra, L. Li, I.R. Dubbelboer, E. Karlsson, B. Pedersen Lomstein, C.A.S. Bergström, Development of a canine artificial colonic mucus model for drug diffusion studies, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2024.106702
  • A. Favaron, E. Turkgeldi, M. Elbadawi, S. Gaisford, A. W. Basit, M. Orlu, Do probiotic interventions improve female unexplained infertility? A critical commentary. Reproductive BioMedicine Online, DOI: 10.1016/j.rbmo.2023.103734
  • A. Favaron, L. E. McCoubrey, M. Elbadawi, A. W. Basit, M. Orlu (2023). The ageing microbiome, pharmaceutical considerations, and therapeutic opportunities. Pharmaceutical Formulations for Older Patients, 191–230, DOI: 10.1007/978-3-031-35811-1_8 
  • I. Parente, L. Chiara, F. Gaiani, G. L. de’Angelis, E. Barocelli, S. Bertoni, P110 Heterogeneous response of colonoid-derived monolayers to TNFα and IFNγ exposure: functional and morphological characterization, Journal of Crohn’s and Colitis, Volume 18, Issue Supplement_1, January 2024, Page i394, DOI: 10.1093/ecco-jcc/jjad212.0240