This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 956851.

Science Communication

COLOTAN Symposia

The COLOTAN 1st Symposium “Colon targeting of drugs: current state of the art” – click to find symposium presentations and recording.

The COLOTAN 2nd Symposium “Drug disposition in the colon” – click to find symposium presentations and recording.

The COLOTAN 3rd Symposium “Gut disorders and possible impact on colonic drug targeting” – click to find symposium presentations and recording.

The COLOTAN 4th Symposium “Targeted drug delivery in the gastrointestinal tract: current status, emerging techniques and blue sky thinking” – click to find symposium programme.

The COLOTAN Closing Conference co-orgnised together with NORDIC POP 2024 in Uppsala – click to find symposium programme.

 

 

Scroll for COLOTAN papers in the below window:

  • L. E. McCoubrey, A. Favaron, A. Awad, M. Orlu, S. Gaisford, A. W. Basit, Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics, Journal of Controlled Release 2023, DOI: 10.1016/j.jconrel.2022.12.029
  • A. L. Nichols, Z. Blumenfeld, L. Luebbert, H. J. Knox, A. K. Muthusamy, J. S. Marvin, C. H. Kim, S. N. Grant, D. P. Walton, B. N. Cohen, R. Hammar, L. L. Looger, P. Artursson, D. A. Dougherty, H. A. Lester, Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane, Journal of Neuroscience, 2023, DOI: https://doi.org/10.1523/JNEUROSCI.1519-22.2022
  • R. Hammar, M. E. Sellin, P. Artursson, Epithelial and microbial determinants of colonic drug distribution, European Journal of Pharmaceutical Sciences, 2023, DOI: 10.1016/j.ejps.2023.106389
  • L. Gnatzy, G. Ismailos, M. Vertzoni, C. Reppas, Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106510
  • K. T. Kopp, L. Saerens, J. Voorspoels, G. Van den Mooter, Solidification and oral delivery of biologics to the colon- A review, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2023.106523
  • V. Barmpatsalou, M. Tjakra, L. Li, I.R. Dubbelboer, E. Karlsson, B. Pedersen Lomstein, C.A.S. Bergström, Development of a canine artificial colonic mucus model for drug diffusion studies, European Journal of Pharmaceutical Sciences, DOI: 10.1016/j.ejps.2024.106702
  • A. Favaron, E. Turkgeldi, M. Elbadawi, S. Gaisford, A. W. Basit, M. Orlu, Do probiotic interventions improve female unexplained infertility? A critical commentary. Reproductive BioMedicine Online, DOI: 10.1016/j.rbmo.2023.103734
  • A. Favaron, L. E. McCoubrey, M. Elbadawi, A. W. Basit, M. Orlu (2023). The ageing microbiome, pharmaceutical considerations, and therapeutic opportunities. Pharmaceutical Formulations for Older Patients, 191–230, DOI: 10.1007/978-3-031-35811-1_8 
  • A. Favaron, B. Hens, M. Montanha, M. McAllister, I. Tomaszewska, S. Moustafa, M. Alvarenga de Oliveira, A.l W. Basit, M. Orlu, Can in vitro/in silico tools improve colonic concentration estimations for oral extended-release formulations? A case study with Upadacitinib, Journal of Controlled Release (JCR), DOI: doi.org/10.1016/j.jconrel.2024.04.024
  • A. Favaron, Y. Abdalla, L. E. McCoubrey, L. Prasanna Nandiraju, D. Shorthouse, S. Gaisford, A. W. Basit, M. Orlu, Exploring the interactions of JAK inhibitor and S1P receptor modulator drugs with the human gut microbiome: Implications for colonic drug delivery and inflammatory bowel disease, European Journal of Pharmaceutical Sciences, September 2024, doi.org/10.1016/j.ejps.2024.106845.
  • L.E. McCoubrey, C. Shen, S. MwasambuA. Favaron, N. Sangfuang, S. Thomaidou, M. Orlu, D. Globisch, A. W. Basit, Characterising and preventing the gut microbiota’s inactivation of trifluridine, a colorectal cancer drug, European Journal of Pharmaceutical Sciences, Dec 2024, doi.org/10.1016/j.ejps.2024.106922
  • A. Favaron, Y. Abdalla, A. Basit, M. Orlu, Ai’s role in colon-targeted drug delivery, Expert Opinion on Drug Delivery, 2025, DOI: 10.1080/17425247.2025.2465769