This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 956851.

news

Alessia won 2nd place in the “Explore your Entrepreneurial Idea” program!

What an incredible experience it was for Alessia Favaron (COLOTAN ESR9) to develop her business idea in “Explore your Entrepreneurial Idea” program at UCL! She won 2nd place with her HerBioma venture, dedicated to balancing women’s hormonal health with microbiome science. Congratulations to Nidhi Seegobin who was a finalist in the program, and Ieva Karvelyte who won 3rd place!  

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COLOTAN published an article on the development of a canine artificial colonic mucus model for drug diffusion studies

Development of a canine artificial colonic mucus model for drug diffusion studies V. Barmpatsalou, M. Tjakra, L. Li, I.R. Dubbelboer, E. Karlsson, B. Pedersen Lomstein, C.A.S. Bergström Abstract Colonic mucus is a key factor in the colonic environment because it may affect drug absorption. Due to the similarity of human and canine gastrointestinal physiology, dogs are an established preclinical species ...

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A review on solidification and oral delivery of biologics to the colon

Solidification and oral delivery of biologics to the colon – A review by COLOTAN researcher Katharina Kopp with the supervision of Lien Saerens (Eurofins), Jody Voorspoels (Eurofins) and Guy Van den Mooter (KU Leuven) that has been published recently in the European Journal of Pharmaceutical Sciences. Abstract The oral delivery of biologics such as therapeutic proteins, peptides and oligonucleotides for ...

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Pedro Canhão Costa is nominated as best presenter at the 2023 Johnson & Johnson Global Science Symposium

Pedro, COLOTAN Ph.D. Researcher at J&J Johnson Innovative Medicine, participated in the 2023 Johnson & Johnson Global Science Symposium, where Ph.D. and Postdoctoral fellows, from all parts of the world, gathered in Beerse (Belgium), between October 17th and 19th. He was awarded the “Best Outstanding Talk”, amongst all selected Ph.D. and Postdoctoral participants, for his oral presentation titled: “Human organotypic ...

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Half-time seminar with Marco Tjakra: Artificial colonic mucus for studies of the mucus absorption barrier in vitro

Wednesday 25 October, Marco Tjakra, COLOTAN Early Stage Researcher and PhD student at the Department of Pharmacy and SweDeliver, presented his research on drug dissolution, diffusion and absorption from the human colon with a focus on the role of the colonic mucus layer. It was a hybrid event as one of four half-time seminars organised by the SweDeliver national competence ...

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COLOTAN researcher Theodoros Giakoumis wins Best Online Poster Award at the CoMH Future Research Conference 2023

Theodoros, COLOTAN PhD researcher at UCC, wins the Best Online Poster Award at CoMH Future Research Conference 2023 on his poster entitled “Exploring polysaccharide-based coating for triggering site-specific drug release in the colon: an in vitro and in vivo evaluation”. His research aims to shed light on how the colonic microbiome can be utilized to trigger specific drug release in the ...

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COLOTAN new published article on the challenges and opportunities when managing the clinical effects of drug-induced intestinal dysbiosis

Managing the clinical effects of drug-induced intestinal dysbiosis with a focus to antibiotics: challenges and opportunities L. Gnatzy, G. Ismailos, M. Vertzoni, C. Reppas Abstract The term “intestinal dysbiosis” is used for indicating change(s) of the intestinal microbiota which have been associated with the development of diseases and the deterioration of disease treatments in humans. In this review, documented clinical effects of ...

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